SPOKE-related paper summaries

The Network Medicine Imperative


Network Medicine Imperative and the Need for an International Network Medicine Consortium. Parini P, Altucci L, Balligand JL, Baumbach PDJ, Ferdinandy P, Filetti S, Maron BM, Petrillo E, Silverman EK, Barabási AL, Loscalzo J; International Network Medicine Consortium**. Am J Med. 2020 Apr 19. pii: S0002-9343(20)30340-5.

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The Network Medicine Imperative

This publication reads like a letter to the editor, a very general argument without much specific information... however, these seem to be the major points:

  • disease and health processes are by nature complex and multifactorial, and network medicine better represents this reality than previous reductionism
  • leverages increasing availability of big data
  • promotes multidisciplinary collaboration
  • may enable more efficient and sustainable health care through:
    • drug repurposing
    • personalized treatment
    • revealing strategies for early intervention and prevention
  • please join and/or support the International Network Medicine Consortium!

Consortium Website

The publication didn't say anything about a website, but searching finds intnm.org.

Hrrmmm... this website highlights CoVex from the Baumbach lab: “the first network and systems medicine online data analysis platform that integrates virus-human interaction data for SARS-CoV-2 and SARS-CoV interaction data”