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Citations (partial list)

Structural basis of Gs and Gi recognition by the human glucagon receptor. Qiao A, Han S et al. Science. 2020 Mar 20;367(6484):1346-1352.

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Wrapp D, Wang N et al. Science. 2020 Mar 13;367(6483):1260-1263.

Gene expression and cell identity controlled by anaphase-promoting complex. Oh E, Mark KG et al. Nature. 2020 Mar 5;579(7797):136-140.

Structural basis of ligand recognition and self-activation of orphan GPR52. Lin X, Li M et al. Nature. 2020 Mar 5;579(7797):152-157.

Measurement of atom resolvability in cryo-EM maps with Q-scores. Pintilie G, Zhang K et al. Nat Methods. 2020 Mar;17(3):328-334.

Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Stoddard PR, Lynch EM et al. Science. 2020 Feb 28;367(6481):1039-1042.

Structural basis for strand transfer inhibitor binding to HIV intasomes. Passos DO, Li M et al. Science. 2020 Feb 14;367(6479):810-814.

Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy. Shahnawaz M, Mukherjee A et al. Nature. 2020 Feb 13;578(7794):273-277.

Structure of an active human histone pre-mRNA 3'-end processing machinery. Sun Y, Zhang Y et al. Science. 2020 Feb 7;367(6478):700-703.

Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. Dick RA, Xu C et al. PLoS Pathog. 2020 Jan 27;16(1):e1008277.

Volatile and thermally stable polymeric tin trifluoroacetates. Bačić G, Rankine CD et al. Inorg Chem. 2020 Jan 21;59(2):996-1005.

Direct visualization of degradation microcompartments at the ER membrane. Albert S, Wietrzynski W et al. Proc Natl Acad Sci USA. 2020 Jan 14;117(2):1069-1080.

Structural basis of substrate recognition by a polypeptide processing and secretion transporter. Kieuvongngam V, Olinares PDB et al. eLife. 2020 Jan 14;9. pii: e51492.

Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Halpin-Healy TS, Klompe SE et al. Nature. 2020 Jan 9;577(7789):271-274.

Structure of the human metapneumovirus polymerase phosphoprotein complex. Pan J, Qian X et al. Nature. 2020 Jan 9;577(7789):275-279.

HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry. Gourh P, Safran SA et al. Proc Natl Acad Sci USA. 2020 Jan 7;117(1):552-562.

The Dundee Resource for Sequence Analysis and Structure Prediction. MacGowan SA, Madeira F et al. Protein Sci. 2020 Jan;29(1):277-297.

Propagation of holes and electrons in metal-organic frameworks. Kriebel M, Hennemann M et al. J Chem Inf Model. 2019 Dec 23;59(12):5057-5064.

Cryo-EM structures of apo and antagonist-bound human Cav3.1. Zhao Y, Huang G et al. Nature. 2019 Dec 19;576(7787):492-497.

Experimental evidence of solvent-separated ion pairs as metastable states in electrostatic interactions of biological macromolecules. Yu B, Pettitt BM, Iwahara J. J Phys Chem Lett. 2019 Dec 19;10(24):7937-7941.

Structure and drug resistance of the Plasmodium falciparum transporter PfCRT. Kim J, Tan YZ et al. Nature. 2019 Dec 12;576(7786):315-320.

A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Steichen JM, Lin YC et al. Science. 2019 Dec 6;366(6470):eaax4380.

Molecular insight into RNA polymerase I promoter recognition and promoter melting. Sadian Y, Baudin F et al. Nat Commun. 2019 Dec 5;10(1):5543.

Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus. Fu G, Zhao L et al. J Cell Biol. 2019 Dec 2;218(12):4236-4251.

The structure and oxidation of the eye lens chaperone αA-crystallin. Kaiser CJO, Peters C et al. Nat Struct Mol Biol. 2019 Dec;26(12):1141-1150.

Antibodies against Plasmodium falciparum malaria at the molecular level. Julien JP, Wardemann H. Nat Rev Immunol. 2019 Dec;19(12):761-775.

Cryo-electron microscopy targets in CASP13: Overview and evaluation of results. Kryshtafovych A, Malhotra S et al. Proteins. 2019 Dec;87(12):1128-1140.

Hierarchical assembly governs TRIM5α recognition of HIV-1 and retroviral capsids. Skorupka KA, Roganowicz MD et al. Sci Adv. 2019 Nov 27;5(11):eaaw3631.

Structure of the native supercoiled flagellar hook as a universal joint. Kato T, Makino F et al. Nat Commun. 2019 Nov 22;10(1):5295.

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Lawrence RE, Fromm SA et al. Science. 2019 Nov 22;366(6468):971-977.

Structure of the mitochondrial import gate reveals distinct preprotein paths. Araiso Y, Tsutsumi A et al. Nature. 2019 Nov 14;575(7782):395-401.

Calculation of absolute binding free energies between the hERG channel and structurally diverse drugs. Negami T, Araki M et al. Sci Rep. 2019 Nov 12;9(1):16586.

Scaffold subunits support associated subunit assembly in the Chlamydomonas ciliary nexin-dynein regulatory complex. Gui L, Song K et al. Proc Natl Acad Sci USA. 2019 Nov 12;116(46):23152-23162.

Drivers of α-sheet formation in transthyretin under amyloidogenic conditions. Childers MC, Daggett V. Biochemistry. 2019 Nov 5;58(44):4408-4423.

A complete data processing workflow for cryo-ET and subtomogram averaging. Chen M, Bell JM et al. Nat Methods. 2019 Nov;16(11):1161-1168.

Architecture of African swine fever virus and implications for viral assembly. Wang N, Zhao D et al. Science. 2019 Nov 1;366(6465):640-644.

Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate. Halfon Y, Jimenez-Fernandez A et al. Proc Natl Acad Sci USA. 2019 Oct 29;116(44):22275-22281.

Exploring the effectiveness of binding free energy calculations. Mondal D, Florian J, Warshel A. J Phys Chem B. 2019 Oct 24;123(42):8910-8915.

Structural transitions during the scaffolding-driven assembly of a viral capsid. Ignatiou A, Brasilès S et al. Nat Commun. 2019 Oct 24;10(1):4840.

Structure and genome ejection mechanism of Staphylococcus aureus phage P68. Hrebík D, Štveráková D et al. Sci Adv. 2019 Oct 16;5(10):eaaw7414.

Structure and functional implications of WYL domain-containing bacterial DNA damage response regulator PafBC. Müller AU, Leibundgut M et al. Nat Commun. 2019 Oct 11;10(1):4653.

Structural insights into the mechanism of human soluble guanylate cyclase. Kang Y, Liu R et al. Nature. 2019 Oct 10;574(7777):206-210.

Transferrin receptor binds virus capsid with dynamic motion. Lee H, Callaway HM et al. Proc Natl Acad Sci USA. 2019 Oct 8;116(41):20462-20471.

Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases. Kondo Y, Ognjenović J et al. Science. 2019 Oct 4;366(6461):109-115.

Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly. Morris KL, Jones JR et al. Nat Struct Mol Biol. 2019 Oct;26(10):890-898.

Structural insights into TRPM8 inhibition and desensitization. Diver MM, Cheng Y, Julius D. Science. 2019 Sep 27;365(6460):1434-1440.

Universal activation index for class A GPCRs. Ibrahim P, Wifling D, Clark T. J Chem Inf Model. 2019 Sep 23;59(9):3938-3945.

Structural basis for inhibition of human primase by arabinofuranosyl nucleoside analogues fludarabine and vidarabine. Holzer S, Rzechorzek NJ et al. ACS Chem Biol. 2019 Sep 20;14(9):1904-1912.

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Brouwer PJM, Antanasijevic A et al. Nat Commun. 2019 Sep 19;10(1):4272.

Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels. Banh R, Cherny VV et al. Proc Natl Acad Sci USA. 2019 Sep 17;116(38):18951-18961.

Tuning metal-metal interactions through reversible ligand folding in a series of dinuclear iron complexes. Zhang S, Wang Q et al. Inorg Chem. 2019 Sep 16;58(18):12234-12244.

Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Fan H, Walker AP et al. Nature. 2019 Sep 12;573(7773):287-290.

Regulation of Eag1 gating by its intracellular domains. Whicher JR, MacKinnon R. eLife. 2019 Sep 6;8. pii: e49188.

The 4-electron cleavage of a N═N double bond by a trimetallic TiNi2 complex. Dunn PL, Chatterjee S et al. Inorg Chem. 2019 Sep 3;58(17):11762-11772.

The central role of the tail in switching off 10S myosin II activity. Yang S, Lee KH et al. J Gen Physiol. 2019 Sep 2;151(9):1081-1093.

Current understanding of the role of neuronal calcium sensor 1 in neurological disorders. Bandura J, Feng ZP. Mol Neurobiol. 2019 Sep;56(9):6080-6094.

Methods for merging data sets in electron cryo-microscopy. Wilkinson ME, Kumar A, Casañal A. Acta Crystallogr D Struct Biol. 2019 Sep 1;75(Pt 9):782-791.

Atomic structure of the Epstein-Barr virus portal. Machón C, Fàbrega-Ferrer M et al. Nat Commun. 2019 Aug 29;10(1):3891.

Structural and functional analyses of photosystem II in the marine diatom Phaeodactylum tricornutum. Levitan O, Chen M et al. Proc Natl Acad Sci USA. 2019 Aug 27;116(35):17316-17322.

Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Zhou L, Sazanov LA. Science. 2019 Aug 23;365(6455). pii: eaaw9144.

Structures of the rhodopsin-transducin complex: Insights into G-protein activation. Gao Y, Hu H et al. Mol Cell. 2019 Aug 22;75(4):781-790.e3.

Modulation of cardiac ryanodine receptor 2 by calmodulin. Gong D, Chi X et al. Nature. 2019 Aug 15;572(7769):347-351.

In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. He Y, Shivakoti S et al. Proc Natl Acad Sci USA. 2019 Aug 13;116(33):16535-16540.

Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant. Halfon Y, Matzov D et al. Sci Rep. 2019 Aug 7;9(1):11460.

Continuous Evaluation of Ligand Protein Predictions: A weekly community challenge for drug docking. Wagner JR, Churas CP et al. Structure. 2019 Aug 6;27(8):1326-1335.e4.

A visualization tool for cryo-EM protein validation with an unsupervised machine learning model in Chimera platform. Chen L, Baker B et al. Medicines. 2019 Aug 6; 6(3):86.

Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Cooney I, Han H et al. Science. 2019 Aug 2;365(6452):502-505.

Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Twomey EC, Ji Z et al. Science. 2019 Aug 2;365(6452). pii: eaax1033.

The pigment-protein network of a diatom photosystem II-light-harvesting antenna supercomplex. Pi X, Zhao S et al. Science. 2019 Aug 2;365(6452). pii: eaax4406.

Identification of Ebola virus inhibitors targeting GP2 using principles of molecular mimicry. Singleton CD, Humby MS et al. J Virol. 2019 Aug 1;93(15). pii: e00676-19.

A cryo-FIB lift-out technique enables molecular-resolution cryo-ET within native Caenorhabditis elegans tissue. Schaffer M, Pfeffer S et al. Nat Methods. 2019 Aug;16(8):757-762.

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Faelber K, Dietrich L et al. Nature. 2019 Jul 18;571(7765):429-433.

Structural basis for the adsorption of a single-stranded RNA bacteriophage. Meng R, Jiang M et al. Nat Commun. 2019 Jul 16;10(1):3130.

Structural visualization of key steps in nucleosome reorganization by human FACT. Mayanagi K, Saikusa K et al. Sci Rep. 2019 Jul 15;9(1):10183.

Cryo-EM structure of oxysterol-bound human Smoothened coupled to a heterotrimeric Gi. Qi X, Liu H et al. Nature. 2019 Jul 11;571(7764):279-283.

Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble. Liu TY, Liu JJ et al. Nat Commun. 2019 Jul 5;10(1):3001.

Large plasticity in magnesium mediated by pyramidal dislocations. Liu BY, Liu F et al. Science. 2019 Jul 5;365(6448):73-75.

Arabinose alters both local and distal H-D exchange rates in the Escherichia coli AraC transcriptional regulator. Tischer A, Brown MJ et al. Biochemistry. 2019 Jul 2;58(26):2875-2882.

Fusion of DARPin to aldolase enables visualization of small protein by cryo-EM. Yao Q, Weaver SJ et al. Structure. 2019 Jul 2;27(7):1148-1155.e3.

Biological adaptations in the Arctic cervid, the reindeer (Rangifer tarandus). Lin Z, Chen L et al. Science. 2019 Jun 21;364(6446). pii: eaav6312.

Two-step activation mechanism of the ClpB disaggregase for sequential substrate threading by the main ATPase motor. Deville C, Franke K et al. Cell Rep. 2019 Jun 18;27(12):3433-3446.e4.

Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Gu J, Zhang L et al. Science. 2019 Jun 14;364(6445):1068-1075.

In situ structure and assembly of the multidrug efflux pump AcrAB-TolC. Shi X, Chen M et al. Nat Commun. 2019 Jun 14;10(1):2635.

Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus. Ilca SL, Sun X et al. Nature. 2019 Jun 13;570(7760):252-256.

Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome. Liu YT, Jih J et al. Nature. 2019 Jun 13;570(7760):257-261.

The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Fu Z, Indrisiunaite G et al. Nat Commun. 2019 Jun 12;10(1):2579.

Multifunctional graphene supports for electron cryomicroscopy. Naydenova K, Peet MJ, Russo CJ. Proc Natl Acad Sci USA. 2019 Jun 11;116(24):11718-11724.

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism. Fumagalli M, Camus SM et al. eLife. 2019 Jun 4;8. pii: e41517.

Structural basis for the clamping and Ca2+ activation of SNARE-mediated fusion by synaptotagmin. Grushin K, Wang J et al. Nat Commun. 2019 Jun 3;10(1):2413.

Breaking the law: unconventional strategies for antibody diversification. Kanyavuz A, Marey-Jarossay A et al. Nat Rev Immunol. 2019 Jun;19(6):355-368.

Structural dynamics of bacteriophage P22 infection initiation revealed by cryo-electron tomography. Wang C, Tu J et al. Nat Microbiol. 2019 Jun;4(6):1049-1056.

The structure of the stress-induced photosystem I-IsiA antenna supercomplex. Toporik H, Li J et al. Nat Struct Mol Biol. 2019 Jun;26(6):443-449.

In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Ding K, Celma CC et al. Nat Commun. 2019 May 17;10(1):2216.

An ultra-stable gold-coordinated protein cage displaying reversible assembly. Malay AD, Miyazaki N et al. Nature. 2019 May 16;569(7756):438-442.

Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Dodonova SO, Prinz S et al. Proc Natl Acad Sci USA. 2019 May 14;116(20):10048-10057.

Predicting protein dimer structures using MELD × MD. Brini E, Kozakov D, Dill KA. J Chem Theory Comput. 2019 May 14;15(5):3381-3389.

Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Maeda S, Qu Q et al. Science. 2019 May 10;364(6440):552-557.

Visualization of clustered protocadherin neuronal self-recognition complexes. Brasch J, Goodman KM et al. Nature. 2019 May 9;569(7755):280-283.

Three-dimensional architecture of epithelial primary cilia. Sun S, Fisher RL et al. Proc Natl Acad Sci USA. 2019 May 7;116(19):9370-9379.

A compact synthetic pathway rewires cancer signaling to therapeutic effector release. Chung HK, Zou X et al. Science. 2019 May 3;364(6439). pii: eaat6982.


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