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Research and development is a major activity at the RBVI. Our goal for core and collaborative research projects is to advance the frontiers of biomedical research while developing new applications of immediate use to scientists. Below are descriptions and links to our core research and development projects and various collaborative research projects.
Design Element

Technological Research and Development Projects

Chimera, an Extensible Molecular Modeling System
Tools for Integrated Sequence/Structure Analysis
Structure-Function Linkage Database
Software for Interactive Analysis of Large Molecular Assemblies
Integrated Visualization and Analysis of Biological Context
Older Research Projects
Design Element

Collaborative Research Projects

Integrating Chimera Into the NRAMM Automated Processing Pipeline
Correlative Light and Electron Microscopy: Visualization of molecular machines in their native cell and tissue context
Visualization of Biological Assemblies at Intermediate Resolution
CryoEM Studies of Viruses
Data Management at the RCSB-PDB
Electron Microscopy Databank
Three Dimensional Structure of Chromosomes
Protein Modeling by Satisfaction of Spatial Restraints
Structure-Based Inhibitor Discovery
Pharmacogenetics of Membrane Transporters
The International Genetrap Consortium
Deciphering Enzyme Specificity
Integration of Methods for Structural Analysis of Functional Sites: Active Site Profiling and Fuzzy Functional Forms
Foundations for Genomic Enzymology: Families, Superfamilies, and Suprafamilies
Dissemination of Bioinformatics Tools from Genentech

Collaborative Research Opportunities

One of the key missions of our Center is to provide collaborative research opportunities for solving a wide range of molecular visualization problems. (See Laboratory Overview.) Collaborative projects bring our expertise in developing computational and visualization tools together with the biomedical expertise of outside scientists. Such efforts can lead to joint publications. Although our resources are limited, we welcome inquiries from scientists interested in collaborating. Inquiries should be directed to Prof. Thomas Ferrin, Director. It would be helpful to include a synopsis of your proposed project in your e-mail.

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