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Featured Citations

Development of a prototype system for archiving integrative/hybrid structure models of biological macromolecules. Vallat B, Webb B et al. Structure. 2018 Jun 5;26(6):894-904.e2.

ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps. Croll TI. Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6).

Structure, mechanism, and regulation of the chloroplast ATP synthase. Hahn A, Vonck J et al. Science. 2018 May 11;360(6389). pii: eaat4318.

Virtual-reality applications give science a new dimension. Matthews D. Nature. 2018 Apr 30; 557:127-128.

Modular assembly of the nucleolar pre-60S ribosomal subunit. Sanghai ZA, Miller L et al. Nature. 2018 Apr 5;556(7699):126-129.

See also: RCSB PDB Images
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News

August 7, 2018

ChimeraX version 0.7 is available. See the change log for what's new.

July 13, 2018

New Virtual Reality at UCSF website shares information on VR projects, resources, and related issues.

April 6, 2018

ChimeraX version 0.6 is available. See the change log for what's new.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX development is supported in part by grants from the National Institutes of Health (currently R01-GM129325, previously P41-GM103311).

Feature Highlight

DNA/protein complex with struts

Struts for 3D Printing

Structures can be reinforced for 3D printing with pseudobonds. In this DNA-transcription factor complex (PDB 5ego), proteins are shown as ribbons and the DNA as a molecular surface. The pseudobonds in blue were read in from a manually created file, 5ego.pb, and further reinforcements in light gray were added automatically with the struts command. For image setup other than orientation, see the command file struts.cxc.

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Example Image

neuraminidase flowers

Potassium Channel-Calmodulin Complex

KCNQ1 is the pore-forming subunit of a cardiac potassium channel. It binds to calmodulin, and mutations in either of these proteins can cause congenital long QT syndrome, a dangerous propensity for irregular heartbeats. In the image, a structure of the KCNQ1/calmodulin complex (PDB 5vms) has been assembled into the native tetrameric form with the sym command. The view is from the cytoplasmic side, with KCNQ1 shown as surfaces, calmodulin as cartoons, and calcium ions as balls. A pastel palette from ColorBrewer has been used to color the surfaces, darkened with color modify for the cartoons, and “rotated” 45° in hue for the ions. See the command file colormod.cxc.

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