Crystal structure of the metazoan Nup62·Nup58·Nup54 nucleoporin complex. Chug H, Trakhanov S et al. Science. 2015 Oct 2;350(6256):106-10.
Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus. Liu H, Cheng L. Science. 2015 Sep 18;349(6254):1347-50.
Structure of a yeast spliceosome at 3.6-angstrom resolution. Yan C, Hang J et al. Science. 2015 Sep 11;349(6253):1182-91.
In situ structural analysis of Golgi intracisternal protein arrays. Engel BD, Schaffer M et al. Proc Natl Acad Sci USA. 2015 Sep 8;112(36):11264-9.
Structural insights into the bacterial carbon-phosphorus lyase machinery. Seweryn P, Van LB et al. Nature. 2015 Sep 3;525(7567):68-72.(Previously featured citations...)
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July 23, 2015
Chimera production release 1.10.2 is now available. Fixes include code signing for Mac OS X installation. The 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
January 9, 2015
Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
November 5, 2014
Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
Volume data can be shown a single plane (or slab) at a time with the Planes feature in Volume Viewer. Plane display can be set to oscillate along the data X, Y, or Z axis, or the plane location can be specified interactively with a slider.(More features...)
Mutations that inactivate the tumor suppressor p53 are found in over 50% of human cancers, and most of the cancer-associated mutations are within its DNA-binding domain. The image shows a tetramer of the p53 DNA-binding domain complexed with DNA (Protein Data Bank entry 2ac0). The tetramer subunits are shown as light blue, green, orange, and yellow ribbons, with red spheres marking several major "hot spots" of mutation. The DNA is shown in purple and blue. (More samples...)