The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling. Zelter A, Bonomi M et al. Nat Commun. 2015 Nov 12;6:8673.
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome. Cordeddu V, Yin JC et al. Hum Mutat. 2015 Nov;36(11):1080-7.
Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Jiang J, Chan H et al. Science. 2015 Oct 30;350(6260):aab4070.
Evolution of an archaeal virus nucleocapsid protein from the
CRISPR-associated Cas4 nuclease.
Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Zhang L, Chen S et al. Science. 2015 Oct 23;350(6259):404-9.(Previously featured citations...)
Chimera SearchGoogle Search
July 23, 2015
Chimera production release 1.10.2 is now available. Fixes include code signing for Mac OS X installation. The 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
January 9, 2015
Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
November 5, 2014
Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)