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Recent Citations

Structural basis of the nucleosome transition during RNA polymerase II passage. Kujirai T, Ehara H et al. Science. 2018 Nov 2;362(6414):595-598.

Cross-linked peptide identification: A computational forest of algorithms. Yılmaz Ş, Shiferaw GA et al. Mass Spectrom Rev. 2018 Nov;37(6):738-749.

Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA+ protease FtsH. Uthoff M, Baumann U. J Struct Biol. 2018 Nov;204(2):199-206.

Hierarchical organization endows the kinase domain with regulatory plasticity. Creixell P, Pandey JP et al. Cell Syst. 2018 Oct 24;7(4):371-383.e4.

The structure and dynamics of C. elegans tubulin reveals the mechanistic basis of microtubule growth. Chaaban S, Jariwala S et al. Dev Cell. 2018 Oct 22;47(2):191-204.e8.

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News

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

July 3, 2018

Chimera production release 1.13 is now available. See the release notes for what's new.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Fly-through Animation

The fly command can animate a flight through molecular structures. Click the example image to fly along the RNA being copied by rotavirus RNA polymerase (PDB 2r7r), an enzyme that replicates the 11 segments of viral RNA. See a video showing how this animation was made.

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Gallery Sample

RNA Bases

Large ribosomal RNA is shown with individual bases depicted using solvent excluded molecular surfaces. Bases A, C, G, U are colored red, yellow, green, and blue. The surfaces were made with the Chimera multiscale tool in combination with the nucleic acid blobs plug-in. The image was raytraced using POVray.

Protein Data Bank model 1s72.

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