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Recent Citations
Structural insights into RNA processing by the human RISC-loading complex. Wang HW, Noland C et.al. Nat Struct Mol Biol. 2009 Nov;16(11):1148-53.
Accuracy analysis of multiple structure alignments. Berbalk C, Schwaiger CS, Lackner P. Protein Sci. 2009 Oct;18(10):2027-35.
10-Å cryoEM structure and molecular model of the Myriapod (Scutigera) 6x6mer hemocyanin: understanding a giant oxygen transport protein. Markl J, Moeller A et.al. J Mol Biol. 2009 Sep 18;392(2):362-80.
Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V. Schmidlin T, Kennedy BK, Daggett V. Biophys J. 2009 Sep 16;97(6):1709-18.
A dimeric structure for archaeal box C/D small ribonucleoproteins. Bleichert F, Gagnon KT et.al. Science. 2009 Sep 11;325(5946):1384-7.
(Previously featured citations...)Chimera Search
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October 14, 2009
A new Chimera production release candidate (version 1.4) is now available. Many new features have been added since the last production release. Please try the release candidate and report any problems.
August 20, 2009
A new Chimera snapshot release is available. This release provides access to many new features added since the last production release, with a greater level of testing than daily builds.
July 3, 2009
SMILES → 3D conversion and fetching modeled 3D structures by PubChem CID have been updated (in daily builds) to use the new REST services provided by the Chemical Informatics and Cyberinfrastructure Collaboratory (CICC) at Indiana University.
(Previous news...)Upcoming Events
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics and funded by the NIH National Center for Research Resources (grant P41-RR01081).
Feature Highlight
Electron density maps can be displayed as mesh or solid isosurfaces with Volume Viewer. Contour levels can be adjusted interactively, multiple levels can be shown for a given map, and display can be restricted to a zone around specified atoms. The image (see how-to) shows PDB entry 2fma and its electron density map. Chimera can fetch the map directly from the Electron Density Server.
(More features...)Gallery Sample
Potassium channel (Protein Data Bank entry 1bl8) on a dark slate blue background with potassium ions shown in firebrick. The channel is comprised of four chains. Each chain has been rainbow-colored from blue at the N-terminus to red at the C-terminus, but only the surface of the channel is shown. The surface has been sliced with a per-model clipping plane. The surface cap color is plum except with opacity set to 0.8. The shininess and brightness have been set to 128 and 8, respectively, and the lights on the scene have been moved from their default positions. The subdivision quality (related to the smoothness of the spherical ions) is 5.0, and the molecular surface was computed with probe radius and vertex density set to 1.0 and 6.0, respectively. (More samples...)