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Featured Citations

PDB-Dev: A prototype system for depositing integrative/hybrid structural models. Burley SK, Kurisu G et al. Structure. 2017 Sep 5;25(9):1317-1318.

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase. Verba KA, Wang RY et al. Science. 2016 Jun 24;352(6293):1542-7.

Structure and membrane remodeling activity of ESCRT-III helical polymers. McCullough J, Clippinger AK et al. Science. 2015 Dec 18;350(6267):1548-51.

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News

August 15, 2017

A second alpha release is available. To help users decide when to update, we have created a change log listing some of the more significant changes and when they occurred.

July 18, 2017

Our ChimeraX paper is accessible online! UCSF ChimeraX: Meeting modern challenges in visualization and analysis. Goddard TD, Huang CC et al.. Protein Sci. 2017, in press.

March 28, 2017

An alpha release of ChimeraX is available (Mac, Linux, Windows). For information on features, please see the documentation.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX development is funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

DNA/protein complex with struts

Struts for 3D Printing

Structures can be reinforced for 3D printing with pseudobonds. In this DNA-transcription factor complex (PDB 5ego), proteins are shown as ribbons and the DNA as a molecular surface. The pseudobonds in blue were read in from a manually created file, 5ego.pb, and further reinforcements in light gray were added automatically with the struts command. For image setup other than orientation, see the command file struts.cxc.

More features...

Example Image

cyclodextrin pore

Cyclodextrin Pore

The outer-membrane protein CymA admits bulky molecules into the periplasmic space of Klebsiella oxytoca. Here, CymA (PDB 4d5d chain A) is depicted in a style reminiscent of a diagnostic X-ray, with transparent molecular surface and β-strand “ribs” in white. The protein has ingested α-cyclodextrin (top) and β-cyclodextrin (bottom), bound at the entry site and near the exit, respectively. Cyclodextrin carbon atoms are shown in blue-gray and oxygen atoms in brick red. For image setup other than orientation, see the command file xray.cxc.

More images...