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Recent Citations

Structure and mechanism of the SGLT family of glucose transporters. Han L, Qu Q et al. Nature. 2022 Jan 13;601(7892):274–279.

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex. Patil DN, Singh S et al. Science. 2022 Jan 7;375(6576):86-91.

Integrative structural modeling of macromolecular complexes using Assembline. Rantos V, Karius K, Kosinski J. Nat Protoc. 2022 Jan;17(1):152-176.

Structure and plasticity of indoleamine 2,3-dioxygenase 1 (IDO1). Röhrig UF, Michielin O, Zoete V. J Med Chem. 2021 Dec 23;64(24):17690-17705.

Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2. Fukudome A, Singh J et al. Proc Natl Acad Sci USA. 2021 Dec 21;118(51):e2115899118.

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News

December 17, 2021

Chimera production release 1.16 is now available. This will be the last release to support Windows 7. See the release notes for what's new.

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

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Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

density display

Density Display

Electron density maps can be read from local files or fetched from databases. Chimera's Volume Viewer allows adjusting contour levels interactively, showing multiple isosurfaces for a given map, and restricting display to a zone around selected atoms. The figure shows PDB entry 2fma and its electron density map. Settings are similar to those described in the Density Display tutorial. See also: Chimera volume display guide

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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