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Recent Citations

Molecular architecture of the human 17S U2 snRNP. Zhang Z, Will CL et al. Nature. 2020 Jul 9;583(7815):310-313.

Protein Structure Modeling from Cryo-EM Map Using MAINMAST and MAINMAST-GUI Plugin. Terashi G, Zha Y, Kihara D. Methods Mol Biol. 2020 Jul 4;2165:317-336.

Structural transitions in influenza haemagglutinin at membrane fusion pH. Benton DJ, Gamblin SJ et al. Nature. 2020 Jul 2;583(7814):150-153.

Cryo-EM structures of inactive and active GABAB receptor. Mao C, Shen C et al. Cell Res. 2020 Jul;30(7):564-573.

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Yin W, Mao C et al. Science. 2020 Jun 26;368(6498):1499-1504.

(Previously featured citations...)

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News

November 13, 2019

Chimera production release 1.14 is now available. See the release notes for what's new.

September 21, 2019

A production release candidate (version 1.14) is available; please try it and report any problems. See the release notes for what's new.

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

(Previous news...)

Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. High-quality images and animations can be generated. Chimera includes complete documentation and is free of charge for academic, government, nonprofit, and personal use. Chimera development was supported by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages. ChimeraX replaces a significant subset of Chimera features, includes several completely new features, and is under active development. Users may certainly choose to use both programs, and it is fine to have both installed.

Feature Highlight

realignment dialog

Multiple Sequence Alignment

Multiple sequence alignment of structure chains in Chimera or realignment of the sequences in an existing alignment can be performed using web services hosted by the UCSF RBVI. The following programs are provided:

The result is automatically shown in Multalign Viewer. (Sequences can also be added to an alignment one by one without a web service, but true multiple sequence alignment is often advantageous.) (More features...)

Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

(More samples...)


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